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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: The quality evaluation system establishment of mesenchymal stromal cells for cell-based therapy products

Fig. 6

The immunomodulatory effects of HUCMSCs were assayed by PBMCs co-culturing with HUCMSCs. HUCMSCs suppressed the activation and differentiations of CD4+ T cells into Th1 and Th17 subpopulations (a, c, ep < 0.001), promoted the maturation of Treg subpopulation in PBMCs induced by IL-2 (b, fp < 0.001), and inhibited CFSE-labeled PBMC proliferation (d, gp < 0.001)

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Stem Cell Research & Therapy

ISSN: 1757-6512