Fig. 6

The immunomodulatory effects of HUCMSCs were assayed by PBMCs co-culturing with HUCMSCs. HUCMSCs suppressed the activation and differentiations of CD4+ T cells into Th1 and Th17 subpopulations (a, c, ep < 0.001), promoted the maturation of Treg subpopulation in PBMCs induced by IL-2 (b, fp < 0.001), and inhibited CFSE-labeled PBMC proliferation (d, gp < 0.001)