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Table 3 Clinic trails of stem cell therapy on influenza virus and CoVs induced lung injury

From: Stem cell therapy: a potential approach for treatment of influenza virus and coronavirus-induced acute lung injury

ID

Cell sources

Virus type

Enrollment

Intervetion

Follow-up

Status

Results

Country

ChiCTR-OCC-15006355

Menstrual blood derived MSCs

H7N9 avian influenza

61 (44/17)

I million cells/kg three times, i.v.

5 years

Completed

MSCs transplantation significantly lowered the mortality

China

NCT02095444

Menstrual blood stem cells

H7N9 avian influenza

20

107 cells/kg, i.v. 4 times in 2 weeks

2.5 years

Unknown

No results posted

China

ChiCTR2000030835

hUC-MSCs

SARS-CoV-2

20

2 or 1 million cells/kg, three times, i.v.

1 year

Recruiting

No results posted

China

ChiCTR2000029990

MSCs

SARS-CoV-2

120 (60/60)

No details

14 months

Recruiting

No results posted

China

NCT04333368

hUC-MSCs

SARS-CoV-2

60

I million cells/kg, three times, i.v.

14 months

Not yet recruiting

No results posted

France

NCT04313322

WJ-MSCs

SARS-CoV-2

5

No details

6 months

Recruiting

No results posted

Jordan

NCT04336254

hDP-MSCs

SARS-CoV-2

20

107 cells/kg, i.v. 3 times in 1 week

1 year

Recruiting

No results posted

China

  1. All information was extracted from http://www.chictr.org.cn/ and https://www.clinicaltrials.gov/
  2. MSCs mesenchymal stem/stromal cells, WJ Wharton’s jelly, i.v. intravenous, DP dental pulp, UC umbilical cord