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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: Tetramethylpyrazine enhanced the therapeutic effects of human umbilical cord mesenchymal stem cells in experimental autoimmune encephalomyelitis mice through Nrf2/HO-1 signaling pathway

Fig. 9

TMP-stimulated hUCMSCs inhibit BBB disruption in EAE mice. a Extravasation of EB dye in whole-mount spinal cords in each group. b Statistical analysis of the fluorescence intensity of EB in each group. c The expression of ZO-1 in the spinal cords of each group. d Relative densitometric analysis of the ZO-1 and β-actin. Columns, mean; bars, SEM. **P < 0.01, ***P < 0.001 compared to PBS treatment. #P < 0.05 compared to hUCMSC treatment alone. The results are representative of three independent experiments

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Stem Cell Research & Therapy

ISSN: 1757-6512

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