Fig. 4From: RETRACTED ARTICLE: Polydatin improves osteogenic differentiation of human bone mesenchymal stem cells by stimulating TAZ expression via BMP2-Wnt/β-catenin signaling pathwayTAZ knockdown offsets the polydatin-induced osteogenic differentiation of hBMSCs. a qPCR was used to test the knockdown efficiency of shTAZ (numbers 1, 2, and 3) at day 14. *p < 0.05 versus the control group; #p < 0.05 versus the shCON group. b The expressions of TAZ protein in different groups were detected by Western blot at day 14. *p < 0.05 versus the control group; #p < 0.05 versus the shCON group. c shTAZ transfection reduced the ALP activities of hBMSCs cultured in OIM with or without PD for 14 days. d shTAZ transfection markedly neutralizes the PD promotional effect on the expression of osteogenic genes (n = 3). *p < 0.05 versus the shCON group; #p < 0.05 versus the shCON+POL group. POL, polydatinBack to article page