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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Bone marrow mesenchymal stem cell-derived endothelial cells increase capillary density and accelerate angiogenesis in mouse hindlimb ischemia model

Fig. 4

Effects of uninduced MSCs and induced MSCs on neovascularization at ischemic sites. On day 28 post-surgery, ischemia samples were analyzed to determine endothelial differentiation and neovascularization of transplanted MSCs at the injured sites. Vessel formation was confirmed by immunofluorescence staining for α-SMA (red) (a) and CD31(b). Scale bar = 75um. c In induced MSCs, GFP+ cells co-localized with α-SMA, indicating vasculature formation from transplanted cells. Scale bar = 50um

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Stem Cell Research & Therapy

ISSN: 1757-6512