Fig. 7From: TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genesChIP analyses of TRF3 at the promoter regions of ME markers at undifferentiated status (ME D0) and ME D1 induction of hESCs. a Gene concept network displaying the representative gene names associated with differentiation or development at ME D1. b Genome browser screenshots of ChIP-seq for T, EOMES, MIXL1, and GSC at the ME D0 and day 1. c ChIP-qPCR analyses of TRF3 at the transcription start sites (TSS) of ME markers (EOMES, T, MIXL1, and GSC) in TRF3−/−-1+vector and TRF3−/−-1+TRF3 hESCs. Data are presented as mean ± SEM. n = 3 each. *p < 0.05, **p < 0.01, ***p < 0.001 compared with the corresponding vector overexpressing values at differentiation day 1Back to article page