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Table 1 ECFCs improved capillary permeability and reduced inflammation after CPB

From: Endothelial colony-forming cells reduced the lung injury induced by cardiopulmonary bypass in rats

  1. Data were collected at pre-CPB and 24 h after CPB. After CPB for 24 h, the PaO2/FiO2 deteriorated. Compared with the CPB group, in the ECFC group, the PaO2/FiO2 was increased. The positive effect of ECFCs on the capillaries was reduced by L-NIO. After CPB for 24 h, the systemic inflammation response was characterized by a significant increase in TNF-α, IL-1β, IL-6, IL-8 and IL-10. Compared to the CPB treatment, ECFCs significantly reduced the concentrations of TNF-α, IL-1β, IL-6 and IL-8 but elevated the levels of IL-10 in the ECFC group. The effect of ECFCs on systemic inflammation was reduced by L-NIO (the data are presented as the mean ± SD)
  2. *P < 0.05 compared with the sham group
  3. #P < 0.05 compared with the CPB group
  4. &P < 0.05 compared with the ECFC group
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Stem Cell Research & Therapy

ISSN: 1757-6512