Fig. 3From: Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathwayhBM-MSC-Ex enhanced the cutaneous wound healing quality. The representative images of H&E staining in the different treatment groups (a). The image quantification of number of cutaneous appendages including hair follicles and sebaceous glands/field (40×) in the healing tissue (b). The blue arrow indicates the presence of sebaceous gland. Immunostaining for α-SMA and VEGF were shown respective images at 16 days after treatment (a). The percentage quantification of α-SMA and VEGF positive area (c, d). The purple arrow indicates the α-SMA-positive cells, and red arrow indicates VEGF positive cells. Scale bar = 1 mm, *p < 0.05, **p < 0.01, ***p < 0.001, n = 8/group, data are reported as mean ± SDBack to article page