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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Adipose mesenchymal stem cell transplantation alleviates spinal cord injury-induced neuroinflammation partly by suppressing the Jagged1/Notch pathway

Fig. 3

The Notch pathway was activated after SCI. a Western blot analysis showing that NICD expression began to increase 1 day after SCI and reached its peak expression 3 days after SCI. GAPDH was used as a loading control. b The quantification of NICD expression (n = 4 in each group; the data are expressed as the mean ± SEM; *P < 0.05 versus the sham group; #P < 0.05 versus 1 day; $P < 0.05 versus 7 days; &P < 0.05 versus 14 days). c Immunostaining of NICD before and 1, 3, 7, and 14 days after SCI. Scale bar = 50 mm. d The quantification of NICD fluorescence intensity (n = 4 in each group; the data are expressed as the mean ± SEM; *P < 0.05 versus the sham group; #P < 0.05 versus 1 day; &P < 0.05 versus 14 days)

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Stem Cell Research & Therapy

ISSN: 1757-6512