Fig. 5From: Intra-carotid arterial transfusion of circulatory-derived autologous endothelial progenitor cells in rodent after ischemic stroke—evaluating the impact of therapeutic time points on prognostic outcomesCellular expressions of angiogenesis factors in brain infarct zone at day 60 after acute IS. a–g Illustrating immunofluorescent (IF) microscopic finding (× 400) for identification of the expression of stromal cell-derived growth factor (SDF)-1α+ cells (green color). Red color in c to g indicated the dye-stained implanted ECPs. h Analytical result of number of SDF-1α+ cells, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. IS. i–o Illustrating IF microscopic finding (× 400) for identification of the expression of CXCR4+ cells (green color). Red color in k to o indicates the dye-stained implanted ECPs. p Analytical result of number of CXCR4+ cells, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. IS. Scale bars in lower right corner represent 20 μm. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple-comparison post hoc test (n = 6 for each group). LCCA = left common carotid artery. SC = sham-operated control; IS = ischemic stroke (IS); EPC3h = EPC administration from LCCA at 3 h after acute IS; EPC3d = EPC administration from LCCA at day 3 after acute IS; EPC7d = EPC administration from LCCA at day 7 after acute IS; EPC14d = EPC administration from LCCA at day 14 after acute IS; EPC28d = EPC administration from LCCA at day 28 after acute ISBack to article page