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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: FNDC5/irisin improves the therapeutic efficacy of bone marrow-derived mesenchymal stem cells for myocardial infarction

Fig. 7

Effects of FNDC5-MSCs on cardiomyocyte apoptosis. a Confocal microscopy showed that TUNEL-positive cardiomyocytes were more frequently observed in the MI group compared with the MI + FNDC5-MSC group. Apoptotic nuclei were identified as TUNEL positive (green fluorescent) and total nuclei by DAPI counterstaining (blue fluorescent). Myocardium was stained using a monoclonal antibody against cTnI (red fluorescent). Scale bar represents 20 μm. b Representative TUNEL-positive apoptotic cells. Data are expressed as means ± SEM; n = 5; *p < 0.05

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