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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Generation of myogenic progenitor cell-derived smooth muscle cells for sphincter regeneration

Fig. 6

Engraftment of mMPC-derived SMC into smooth muscle tissue in vivo. a Quantification of percent desmin- and aSMA-positive cells performed by immunofluorescence staining of two preparations of mMPC-SMC. b Fluorescence signal detection of co-injected fluorescent beads and TdTomato transgene expressing cells localized in the intact pyloric sphincter muscle by IVIS imaging ex situ. c Tissue engraftment and aSMA protein expression of TdTomato-positive mMPC-SMC in pyloric sphincter histological sections of intramuscular-injected SMC 12 weeks after implantation. Representative images of n = 8 injected mice

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