Skip to main content
Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

Fig. 1

Characterization of BMSCs and BMSC-derived extracellular vesicles. a Flow cytometric analysis for detection of BMSC surface markers. b Morphology of BMSCs. Scale bar 100 μm. c Adipogenic, chondrogenic, and osteogenic differentiation potentials of BMSCs. Scale bar 100 μm. d Western blot was used to confirm the expression of EV-specific markers CD9, CD63, and HSP70. e Particle size distribution. f Representative transmission electron microscopy image of BMSC-EVs, showing a typical spheroid shape. Scale bar 100 nm. g Localization of PKH26 fluorescence in the UUO kidney and contralateral kidney. The control group was injected with unlabeled EVs. Scale bar 25 μm. h Localization of PKH67 fluorescence in HK-2 cells was determined by fluorescent microscopy. Scale bar 25 μm

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512