Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Lung delivery of MSCs expressing anti-cancer protein TRAIL visualised with 89Zr-oxine PET-CT

Fig. 5

Comparison of viable MSC location to PET signal. Intravenously injected 89Zr-oxine-labelled uct-MSCs expressing luciferase and ZsGreen were tracked over 7 days using a bioluminescence imaging and b PET-CT imaging. c ROI analysis of PET and BLI data showed a comparable decrease in %ID and photons in the lungs over time (n = 3, error bars SD). At 7 days post-injection, lungs were removed and cryosectioned, before imaging with d autoradiography (scale bar 5 mm) and e fluorescence microscopy (scale bar 200 μm), to confirm the presence of ZsGreen-expressing cells and 89Zr signal within the lungs

Back to article page