Fig. 4

LAP2α is essential for bone formation in vivo. a–c H&E staining (a), Masson’s trichrome staining (b), and immunohistochemical staining of OCN (c) together with histomorphometry analysis of histological sections from implanted hASC-scaffold hybrids, n = 16. Dark-brown granules indicating positive staining are marked by black arrows. Low magnification images are provided in the upper panels, scale bars: 50 μm, while higher magnification images are in the lower panels (a–c), scale bars: 20 μm. Data are shown as the mean ± SD; *P < 0.05 compared with the control group; **P < 0.01 compared with the control group; NS: not significant