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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation

Fig. 8

Adipose-derived stem cell extracellular vesicles (ADSC-EVs) rescued fibroblast (FB) cell cycle arrest. a, b Flow cytometry showing that cell populations in the G1 phases were significantly decreased, whereas those in the S and G2 phases were significantly increased by ultraviolet B (UVB) irradiation. These changes were restored to levels close to those of the control group. c, d Expression of cell cycle arrest-associated proteins P53 and P21 were increased by UVB irradiation and decreased by ADSC-EVs. *P < 0.05 indicated a significant difference; n.s., no significant difference between groups

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