Table 3 Graft details and donor microchimerism rate after GPBSC infusion
Patient | Graft | Donor microchimerism rate (%) | aGVHD | |||||
|---|---|---|---|---|---|---|---|---|
Mononuclear (cells/kg) | CD34+ (cells/kg) | 1 week | 2 weeks | 3 weeks | 4 weeks | Organ system affected | Severity scoring | |
1 | 12.2 | 4.56 | 37.4 | 86.0 | 93.89 | Elevated LFTs, rash, GI symptoms | IV | |
2 | 5.5 | 2.31 | 0.024 | 0.081 | ||||
3 | 9.7 | 2.115 | 0.023 | 0.014 | 0.005 | |||
4 | 5.5 | 2.59 | – | |||||
5 | 5.1 | 1.17 | 0.846 | 0.148 | Elevated LFTs, GI symptoms | II | ||
6 | 5.2 | 2.08 | 0.17 | Elevated LFTs, GI symptoms | II | |||
7 | 6.4 | 1.4 | – | |||||
8 | 11.6 | 2.43 | 0.15 | 0.25 | ||||
9 | 10.1 | 2.4 | – | GI symptoms | I | |||
10 | 9.7 | 4.924 | 11.21 | 0.15 | 0.01 | 0.01 | Elevated LFTs, GI symptoms | II |
11 | 16.4 | 3.19 | – | |||||
12 | 5.3 | 1.325 | 0.002 | 0.001 | Elevated LFTs | I | ||
13 | 9.6 | 3.11 | 0.008 | |||||
14 | 6.1 | 2.04 | – | |||||
15 | 8.8 | 2.65 | – | |||||
16 | 16.5 | 2.31 | 0.37 | 0.31 | 0.034 | |||
17 | 5.1 | 2.448 | – | |||||
18 | 5.7 | 1.824 | 3.26 | 0.76 | Elevated LFTs, GI | II | ||