Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Probucol enhances the therapeutic efficiency of mesenchymal stem cells in the treatment of erectile dysfunction in diabetic rats by prolonging their survival time via Nrf2 pathway

Fig. 4

Probucol activates Nrf2/HO-1 pathway and reduces apoptosis in MSCs. a Representative images of Western blotting of Nrf2 and HO-1 in MSCs treated with different concentrations of probucol. β-Actin was used as a loading control. b Probucol reduced H2O2-induced apoptosis in MSCs. Representative images of Western blotting of Caspase3, Cleaved-Caspase3, Bax, and Bcl-2 in MSCs treated with different concentrations of probucol. β-Actin was used as a loading control. *P < 0.05 and **P < 0.01 indicate significant difference compared with the sham group. #P < 0.05 and ##P < 0.01 indicate significant difference compared with the H2O2-treated group

Back to article page