Fig. 1

Prenatal dexamethasone exposure (PDE) induces bone loss in later life of female mouse offspring. a Representative μCT images of proximal tibia in 12-week-old female and male mouse offspring. Scale bar, 1 mm. Quantitative analyses of tibial microstructural parameters of female mouse offspring including trabecular bone volume fraction (BV/TV) (b), trabecular number (Tb. N) (c), trabecular thickness (Tb. Th) (d), and trabecular separation (Tb. Sp) (e). Quantitative analysis of BV/TV (f), Tb. N (g), Tb. Th (h), and Tb. Sp (i) in tibia of male mouse offspring. Data are represented as mean ± S.E.M. *P < 0.05 versus control (n = 6 per group, Student’s t test)