Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013

Fig. 7

DLX5 and HOXC8 negatively regulated the LINC01013 by binding to the LINC01013 promoter in SCAPs. a LINC01013 was upregulated in DLX5 knocked down or HOXC8 knocked down SCAPs. b LINC01013 was downregulated in DLX5 over-expressed or HOXC8 over-expressed SCAPs. c ChIP assays showed HOXC8 over-expression enhanced the recruitment of HOXC8 into LINC01013 promoter in SCAPs. d ChIP assays showed DLX5 over-expression enhanced the recruitment of HOXC8 into LINC01013 promoter in SCAPs. GAPDH was used as an internal control. One-way ANOVA analysis was performed to determine the statistical significance. All error bars represent s.d. (n = 3). **P ≤ 0.01. Consh, control shRNA; DLX5sh, DLX5 shRNA; HOXC8sh, HOXC8 shRNA

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512