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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013

Fig. 8

LINC01013 knock-down enhanced the chondrogenic differentiation in SCAPs. a Real-time RT-PCR results showed LINC01013 knock-down in SCAPs. b, c Alcian Blue staining and quantitative analysis results showed that knock-down of LINC01013 promoted chondrogenic differentiation in SCAPs. df Real-time RT-PCR results showed that knock-down of LINC01013 upregulated the expressions of COL2 (d), COL5 (e), and SOX9 (f) in SCAPs. g Alcian Blue and Picro Sirius Red staining results of chondrogenesis induced pellet. Scale bar, 100 μm. GAPDH was used as an internal control. Student’s t test was performed to determine the statistical significance. All error bars represent s.d. (n = 3). *P ≤ 0.05. **P ≤ 0.01. Consh, control shRNA; LINC01013sh, LINC01013 shRNA

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