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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease

Fig. 4

Representative micrographs of collagen expression in rat UUO kidney sections with Masson’s trichrome (MT) staining from different experimental groups (magnification, × 200). a Young and old rats were subjected to unilateral ureteral obstruction (UUO), and MT staining was used to analyse the changes in collagen expression of young or old MSC-EVs treatment at 7 and 14 days after surgery. b Young and old rats were subjected to unilateral ureteral obstruction (UUO), and MT staining was used to analyse the changes in collagen expression of LV-miR-294/133 inhibitor/mimic treatment at an end point of 7 and 14 days after surgery. c–e The quantitative analysis of collagen expression in the kidneys. All data are represented as the mean ± SE. The rat number in each group is 5. *p < 0.05 compared with the UUO group

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