Fig. 4From: Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney diseaseRepresentative micrographs of collagen expression in rat UUO kidney sections with Masson’s trichrome (MT) staining from different experimental groups (magnification, × 200). a Young and old rats were subjected to unilateral ureteral obstruction (UUO), and MT staining was used to analyse the changes in collagen expression of young or old MSC-EVs treatment at 7 and 14 days after surgery. b Young and old rats were subjected to unilateral ureteral obstruction (UUO), and MT staining was used to analyse the changes in collagen expression of LV-miR-294/133 inhibitor/mimic treatment at an end point of 7 and 14 days after surgery. c–e The quantitative analysis of collagen expression in the kidneys. All data are represented as the mean ± SE. The rat number in each group is 5. *p < 0.05 compared with the UUO groupBack to article page