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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration

Fig. 4

Gene expression in the mesenchymal stem cell (MSC) aggregate cultures. The relative expressions of ACAN, COL1A1, COL2A1, and SOX9 by real-time RT-PCR on days 14 and 21 after aggregation. mRNA levels were normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) levels and are presented as fold changes compared to MSC aggregates alone. Data are shown as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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