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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human amnion mesenchymal stem cells restore spermatogenesis in mice with busulfan-induced testis toxicity by inhibiting apoptosis and oxidative stress

Fig. 4

hAMSCs ameliorated cell apoptosis and improved cell proliferation and spermatocyte meiosis in a busulfan-induced testis toxicity mouse model. a, b Fluorescence microscopy was employed to detect the relative fluorescence intensity of TUNEL (red) and SCP3 (green) in the three groups. c–f The protein expression of SURVIVIN, BCL2, CASPASE3, and CASPASE9 was evaluated in the three groups by western blot. The results are presented as the mean ± SD. ***p < 0.001 (compared to the BSF group). n = 10 for each group

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