Fig. 3

BM-MSCs and ASCs suppressed bacterial growth. Inhibition of bacterial growth upon exposure to a BM-MSCs and b ASCs. Cont, control medium; CM, conditioned medium. c Representative images of assay plates. BM-MSCs or ASCs were cultured in the growth medium, and three experimental groups inoculated with bacteria were prepared and analyzed: (1) culture medium alone, (2) conditioned medium from BM-MSCs or ASCs, (3) conditioned medium from BM-MSCs or ASCs containing cells, and (4) unconditioned culture medium containing BM-MSCs/ASCs. The total contents of each well (bacteria and medium) were plated for bacterial colony counting. CFU formation after 16–18 h were quantified, and the results compared to the bacteria control and expressed as percentages (mean + SD). For human ASCs, data are from 9 to 12 patients (n = 27 to 36), and for BM-MSCs, 2 patients (n = 12–21)