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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway

Fig. 1

Characterization and internalization of sEV. a, d TEM showed that the sEV presented with the typical morphology. Scale bar, 100 nm. b NTA revealed that the peak diameter of BMMSC-sEV was 138.8 nm. c, f The western blot results showed that CD9 and CD81 were enriched in sEV but were undetectable in the cells. e The peak diameter of NRK-52E-sEV was 134.7 nm. g The laser scanning confocal images showed that fibroblasts internalized PKH26-labeled sEV after 24 h. The nuclei were stained blue, the sEV were stained red, and the cytoskeleton was stained green. Scale bars, 100 μm and 50 μm

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