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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway

Fig. 5

Identifying miRNAs enriched in BMMSC-sEV. a Heat map of differentially expressed miRNAs between BMMSC-sEV and NRK-52E-sEV showed that a total of 18 miRNAs were abundant in BMMSC-sEV. b KEGG pathway classification of upregulated miRNA target genes. c Top 30 enriched GO terms of enriched miRNA target genes. d qRT-PCR analysis showed that four of seven abundant miRNAs in BMMSC-sEV were in accordance with miRNA sequencing, including rno-miR-328a-3p, rno-miR-143-3p, rno-miR-125b-1-3p, and rno-miR-674-3p. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Stem Cell Research & Therapy

ISSN: 1757-6512