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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway

Fig. 7

Exosome-MS regulates HPDLSC osteogenic differentiation by miR-181b-5p. Inhibiting or overexpressing miR-181b-5p changes the osteoblast differentiation ability of HPDLSCs with LPS stimulation between the Exosome and Exosome-MS groups. a ALP staining (scale bar 100 μm) and Alizarin red staining (scale bar 200 μm). b, c Quantitative analysis of staining using ImageJ. d–g The expression of genes including PIK3CA, AKT1, Runx2, and BMP2

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