Fig. 5

The effect of ASCs on granulation tissue formation. a H&E staining at day 7 and 14 post-wounding in Chow or T2D mice receiving PBS, C57BL/6 ASCs, or T2D ASCs. b The number of epidermal sleeves in mice from different groups. c The length of epidermal sleeves in mice at 14 days post-wounding. d Immunohistochemical staining of CD34⁺ cells in wound tissue at 7 and 14 days post-treatment. e Vessel areas in mice from different groups at 7 and 14 days post-treatment. f Deposition of collagen III in granulation tissue of 2 groups of mice. T2D: mice fed high-fat diet receiving STZ injection; C57BL/6: mice fed standard diet. At least 3 mice were used in each group. *P < 0.05, **P < 0.01, ANOVA test