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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

Fig. 2

ATV-Exos facilitated endothelial cell angiogenesis in vitro. a The proliferation of HUVEC incubated with complete culture medium supplemented with LG, HG, HG + Exos, and HG + ATV-Exos for 1, 3, and 7 days. b The images of migration ability as well as tube formation of HUVEC. c Quantitative analysis of cell migration of four groups. d Quantitative analysis of tube formation of four groups. e The VEGF concentration of supernatant in different media supplemented with LG, HG, HG + Exos, and HG + ATV-Exos through Elisa. f The relative expression level of ANG1, PDGF, bFGF, and EGF of HUVEC examined by qRT-PCR. *P < 0.05

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