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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

Fig. 3

ATV-Exos accelerated the wound healing of STZ-induced diabetic rats. a Experimental design of the animal study. b Representative images of full-thickness defects and wound healing rates of the STZ-treated rats receiving a multipoint injection of PBS (control), Exo, and ATV-Exo at days 0, 3, 7, and 14 day postoperatively. *P < 0.05 versus control, #P < 0.05 versus Exos. c H&E staining (black arrows indicate neuroepithelium) and quantification of wound length at day 7 and 14. Scale bars = 2 mm. d Masson’s trichrome staining at day 7 and 14 postoperatively at a magnification of × 100 and × 400. *P < 0.05

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