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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

Fig. 4

ATV-Exos ameliorated the aberrant vascularization of diabetic rats in vivo. a The representative images of microfil perfusion around the wound and quantitative analysis of vessel area and length in the control, Exo, and ATV-Exo groups. b Upper: Immunohistochemical analysis of newly developed vessels stained by CD31 at day 7 and 14 (red arrows represent vessels.). Scale bars = 100 μm. Middle: Immunofluorescence assessment of blood vessels stained by CD31/α-SMA at day 7 and 14. Lower: Quantitative analysis of blood vessel numbers per field by immunohistochemistry and immunofluorescence at days 7 and 14. *P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512