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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway

Fig. 3

miR-137 level in oxyHb-treated SH-SY5Y cells was decreased and improved after EPC-EXsmiR-137 transfection. a Representative micrographs showed miR-137 could be transfected into SH-SY5Y cells via EPC-EXs. b Fluorescence intensity of miR-137 was comparable between the control and oxyHb groups after the EPC-EXsmiR-137 transfection, n = 6. c Lentiviral miR-137 transfection increased the miR-137 in EPCs, n = 6. d Lentiviral miR-137 transfection increased the miR-137 in EPC-EXs, n = 6. e EPC-EXsmiR-137 increased the deteriorative miR-137 level in oxyHb-treated SH-SY5Y cells, n = 6. *P < 0.01 and **P < 0.01

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