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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway

Fig. 4

EPC-EXsmiR-137 alleviated the oxyHb-induced apoptosis in SH-SY5Y cells. a Quantitative analysis of cell viability was detected by the MTT assay in each group, n = 6. b Representative bands of Cyt-C, cleaved caspase-3, and β-actin proteins in western blot revealed the different expression in each group; the densities of the protein bands were normalized to β-actin. c Quantification of relative expression of Cyt-C in each group, n = 4. d Quantification of relative expression of cleaved caspase-3 in each group, n = 4. e Representative Annexin V/PE staining result measured by flow cytometry. f Summarized data of the apoptosis rate in each group, n = 4. *P < 0.01 and **P < 0.01

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