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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway

Fig. 9

Activation of COX2/PGE2 pathway abolished the protection of EPC-EXsmiR-137 against ferroptosis. a Representative micrographs of lipid peroxidation stain in SH-SY5Y cells of each group. b Quantitative analysis of the relative level of lipid peroxidation in each group, n = 6. c Quantitative analysis of GSH content in the SH-SY5Y cells of each group, n = 6. d Representative bands of GPx4 and β-actin proteins measured by western blot. e Quantification of GPx4 expression in each group, β-actin served as the reference protein, n = 5. f Representative micrographs of iron staining in the SH-SY5Y cells of each group. g Quantitative analysis of iron deposition in the cells from different groups, n = 4. *P < 0.01 and **P < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512