Fig. 2From: Dental follicle stem cells rescue the regenerative capacity of inflamed rat dental pulp through a paracrine pathwayrDFSC-CM attenuated inflammation in LPS-stimulated rDPCs. Cells were cultured in rDFSC-CM or αMEM with or without 0.5 mg/L LPS for 3, 6, and 9 h. As demonstrated by real-time PCR, rDFSC-CM treatment decreased the expression of IL-1β (a), IL-6 (b), and TNF-α (c); elevated the expression of IL-4 (d) and TGF-β (e); and downregulated the level of IL-10 (f). β-Actin was used as an internal control. The data are presented as the means ± SDs from three independent experiments. *P < 0.05, **P < 0.01Back to article page