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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: MicroRNA-503-3p affects osteogenic differentiation of human adipose-derived stem cells by regulation of Wnt2 and Wnt7b under cyclic strain

Fig. 3

The cyclic strain induced osteogenic differentiation of hASCs. (*p < 0.05, there were significant differences between these two groups) a After cyclic strain loading for 6 days, the mRNA expression of RUNX2, ALP, SPARC, Wnt7b, and β-catenin were significantly increased, compared to hASCs without cyclic strain loading. b Protein blots were listed in the left column. After cyclic strain loading for 6 days, the protein expression of RUNX2, ALP, SPARC, Wnt7b, and β-catenin were significantly increased, compared to hASCs without cyclic strain loading. c After cyclic strain loading for 6 days, both the ALP activity and the content of Ca2+ were increased

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