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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis

Fig. 7

UC-MSC treatment alleviated glomerular and tubulointerstitial fibrosis in DN rats. a Masson’s trichrome staining. b, c Immunofluorescence staining of collagen IV in glomerulus (b) and tubulointerstitium (e). d, e Immunohistochemistry staining of α-SMA (d) and TGF-β (e) in kidney tissues. f The mRNA expression of TGF-β in kidney tissues. g, h Concentration of TGF-β in plasma (g) and kidney (h) tissues. i Western blot analysis of TGF-β in kidney tissues. N = 5 (per group), data are presented as mean ± SEM. *P < 0.05, **P < 0.01 vs control. #P < 0.05 vs DN group

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Stem Cell Research & Therapy

ISSN: 1757-6512