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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Hypoxia alleviates dexamethasone-induced inhibition of angiogenesis in cocultures of HUVECs and rBMSCs via HIF-1α

Fig. 3

Dexamethasone inhibited HUVEC angiogenesis. a Dexamethasone (DEXA) was found to inhibit HUVEC angiogenesis in the Matrigel tube formation assay. Photos were taken after 6 h, and the total length of the blood vessels was quantified by ImageJ. b Growth curve of HUVECs in EGM treated with or without dexamethasone. c The streaked plate assay was used to test the migration ability of HUVECs in EGM with or without dexamethasone. d qRT-PCR was used to detect the expression of angiogenesis-related genes in HUVECs treated with or without dexamethasone at 72 h. *p < 0.05, compared with HUVECs in EGM. ns: p > 0.05, there was no significant difference. n = 3

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Stem Cell Research & Therapy

ISSN: 1757-6512