Fig. 3From: Plasticity of Paneth cells and their ability to regulate intestinal stem cellsSchematic of the model for PC regulation. Wnt signalling upregulates and downregulates Notch signalling, ErbB3, MIST1and Hmgcs2 can promote PC maturation. Notch signalling, mTORCC1 and Lkb1 upregulated or ErbB3, Gαq/Gα11 and PKCλ/ι inactivation inhibit PCs differentiation and functionBack to article page