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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells

Fig. 7

KEGG pathway classification map of the experimental group. Upregulated and downregulated genes were categorized into enriched functional signaling pathways. a All KEGG pathways were first classified into six categories: metabolism (red box), genetic information processing (yellow box), environmental information processing (green box), cellular processes (light blue box), organismal systems (blue box), and human diseases (purple box). These categories were then sub-categorized according to the level of significance. The significance of enrichment maps of these second categories is presented as blue color density. b, c Changes in expression of genes related to the ECM-receptor interaction pathway and PI3K-AKT signaling pathway with serial passaging were evaluated by KEGG enrichment map analysis

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Stem Cell Research & Therapy

ISSN: 1757-6512