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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Reparative effect of mesenchymal stromal cells on endothelial cells after hypoxic and inflammatory injury

Fig. 5

MSC transmigrate through an endothelial monolayer towards kidney injury chemokine SDF-1α. a Schematic representation of the transwell assay to assess the capacity of MSC to transmigrate through a monolayer of endothelial cells. b MSC showed the capacity to transmigrate through a confluent endothelial monolayer towards SDF-1α. Injury of HUVEC enhanced the transmigration capacity of MSC, resulting in 54% of the added MSC transmigrating through the injured HUVEC monolayer after 6 h (n = 5). Results are shown as mean ± SD. Significance of the comparison between injured HUVEC + SDF-1α and non-injured HUVEC + SDF-1α is shown as *p value < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512