Table 1 Change of the structural parameters of the retina according to study timepoints and genetic mutation analysis
Patient No | Genetic mutation | Eye | Horizontal EZW | Vertical EZW | Outer retinal thickness | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
T0 | T1 | T2 | T0 | T1 | T2 | T0 | T1 | T2 | |||
1 | RHO | R | 3.56 | 3.83 | 3.84 | 4.62 | 4.84 | 4.84 | 85.0 | 152.2 | 154.1 |
2 | RP1 | L | 3.21 | 3.34 | 3.38 | 3.36 | 3.41 | 3.42 | 93.4 | 120.4 | 121.8 |
3 | EYS | R | 1.86 | 1.87 | 1.87 | 1.15 | 1.18 | 1.18 | 117.4 | 117.8 | 117.6 |
4 | Unknown | L | 3.93 | 4.14 | 4.12 | 2.72 | 2.74 | 2.74 | 118.2 | 145.4 | 145.6 |
5 | RPGR | L | 1.61 | 1.64 | 1.37 | 1.44 | 1.48 | 1.13 | 103.0 | 105.7 | 101.2 |
6 | Unknown | R | 2.74 | 2.75 | 2.77 | 2.49 | 2.51 | 2.51 | 129.0 | 131.9 | 132.4 |
7 | C2ORF | R | 4.01 | 4.09 | 4.10 | 4.02 | 4.08 | 4.11 | 116.0 | 126.3 | 126.6 |
8 | USH2A | L | 2.61 | 2.65 | 2.64 | 2.45 | 2.62 | 2.61 | 101.4 | 102.2 | 102.0 |
9 | USH2A | L | 3.91 | 3.98 | 3.98 | 3.92 | 3.96 | 3.96 | 79.2 | 135.6 | 134.4 |
10 | RP1 | L | 3.90 | 3.99 | 3.98 | 3.86 | 3.92 | 3.91 | 105.0 | 111.8 | 110.9 |
11 | PDE6B | R | 3.87 | 3.87 | 3.86 | 3.71 | 3.70 | 3.69 | 92.2 | 128.7 | 127.8 |
12 | USH2A | R | 1.02 | 1.04 | 1.04 | 1.09 | 1.17 | 1.17 | 128.2 | 145.6 | 144.8 |
13 | PDE6B | L | 1.15 | 1.18 | 1.18 | 1.13 | 1.13 | 1.13 | 101.0 | 104.8 | 105.6 |
14 | MERTK | R | 2.23 | 2.25 | 2.25 | 2.08 | 2.12 | 2.12 | 100.4 | 110.0 | 110.1 |
15 | PRPF3 | L | 2.18 | 2.22 | 2.23 | 2.14 | 2.20 | 2.21 | 84.8 | 120.0 | 122.8 |
16 | RPGR | R | 2.18 | 2.16 | 2.15 | 2.14 | 2.12 | 2.11 | 128.6 | 98.4 | 96.7 |
17 | PDE6B | L | 2.90 | 2.93 | 2.93 | 1.32 | 1.34 | 1.34 | 105.6 | 122.8 | 122.6 |
18 | TULP1 | L | 1.42 | 1.48 | 1.48 | 1.25 | 1.25 | 1.25 | 89.0 | 94.8 | 96.0 |
19 | USH2A | R | 2.11 | 2.14 | 2.14 | 3.03 | 3.06 | 3.06 | 82.6 | 109.0 | 110.1 |
20 | PDE6B | R | 1.11 | 1.11 | 1.11 | 1.14 | 1.14 | 1.14 | 84.2 | 86.8 | 87.0 |
21 | BBS2 | R | 1.15 | 1.18 | 1.18 | 1.06 | 1.08 | 1.08 | 85.2 | 97.0 | 97.3 |
22 | PRPF3 | L | 2.49 | 2.49 | 2.49 | 2.26 | 2.26 | 2.26 | 86.0 | 116.0 | 115.7 |
23 | RP1 | R | 2.51 | 2.51 | 2.51 | 2.54 | 2.54 | 2.54 | 91.0 | 91.6 | 91.0 |
24 | RHO | L | 3.18 | 3.24 | 3.24 | 3.21 | 3.34 | 3.35 | 118.2 | 152.4 | 152.6 |
25 | RHO | L | 3.26 | 3.28 | 3.28 | 3.14 | 3.16 | 3.16 | 106.0 | 132.8 | 132.7 |
26 | PRPF3 | L | 2.11 | 2.17 | 2.22 | 2.29 | 2.34 | 2.34 | 109.3 | 122.0 | 122.1 |
27 | Unknown | L | 1.78 | 1.80 | 1.80 | 1.66 | 1.66 | 1.66 | 120.2 | 135.8 | 136.2 |
28 | Unknown | R | 1.66 | 1.65 | 1.65 | 1.38 | 1.37 | 1.37 | 116.0 | 122.8 | 120.7 |
29 | EYS | R | 1.48 | 1.48 | 1.47 | 1.51 | 1.50 | 1.50 | 117.0 | 117.0 | 116.8 |
30 | RHO | L | 4.71 | 4.98 | 5.02 | 4.79 | 4.86 | 4.91 | 110.0 | 140.4 | 141.7 |
31 | RHO | R | 4.90 | 4.90 | 4.90 | 3.96 | 3.96 | 3.96 | 101.0 | 106.0 | 106.3 |
RHO | L | 4.71 | 4.70 | 4.70 | 4.00 | 3.98 | 3.98 | 96.9 | 101.3 | 101.0 | |
32 | CERKL | R | 2.57 | 2.60 | 2.60 | 2.44 | 2.44 | 2.44 | 70.4 | 111.8 | 111.6 |
CERKL | L | 1.98 | 2.00 | 1.98 | 1.87 | 1.87 | 1.86 | 72.6 | 112.4 | 112.0 | |