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Table 4 Comparison of functional measurements according to inheritance pattern

From: Management of retinitis pigmentosa by Wharton’s jelly-derived mesenchymal stem cells: prospective analysis of 1-year results

Inheritance

BCVA

FPDI

T0

T2

p

T0

T2

p

AD n = 12

81.8 ± 11.8

91.6 ± 12.2

0.01*

8.9 ± 2.7

13.2 ± 2.9

0.01*

AR n = 16

61.7 ± 10.9

72.9 ± 10.5

0.01*

8.1 ± 2.7

11.7 ± 2.7

0.01*

X-linked n = 2

65.0 ± 0

63.5 ± 0

0.09

4.5 ± 0

4.5 ± 0

0.1

Comparison**

pAR = pAD > pX-linked

pAD > pAR > pX-linked

  1. **Sidak binary comparison test; *p < 0.05, statistically significant
  2. AD autosomal dominant, AR autosomal recessive, X-linked X-related inheritance pattern, BCVA best corrected visual acuity (ETDRS letters), FPDI fundus perimetry deviation index (%), T0 (baseline) just before the Wharton jelly-derived mesenchymal stem cell injection, T2 12th month after injection
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Stem Cell Research & Therapy

ISSN: 1757-6512