Table 1 Summary of MSC transcriptomic lineage marker expression by MSCs during prolonged culture or licensing
Roson-Burgo core signature | Rohart MSC test | ||
|---|---|---|---|
Assessed | 445/489 (91%) | 11/16 (69%) | |
Passage 2–12 UC-MSCs | Reliable | 435/445 (98%) | 4/11 (36%) |
Resting and primed UC and BM-MSCs | Reliable | 436/445 (98%) | 5/11 (45%) |
Overlap | Reliable | 433 | 4 (CXCL2, GDF5, MBD2, PRRX1) |
Unreliable | 7 (ADAMTS5, DACT1, IGFBP5, ISLR, LAMA4, LMO7, SMIM14) | 6 (CES1P1, ABI3BP, C1orf115, HSPB3, OMD, SAA2) |