Skip to main content

Table 1 Demographic and laboratory data of the investigated pediatric β-thalassemia patients

From: CRISPR-mediated gene modification of hematopoietic stem cells with beta-thalassemia IVS-1-110 mutation

Variable

Case 1

Case 2

Case 3

Case 4

Case 5

Case 6

Age (years)

10 years

8 years

2 years

1.5 years

4 years

3 years

Gender

Male

female

Female

Male

Female

Male

Duration of blood transfusion

8 years

7 years

1.5 years

1 year

3 years

2.5 years

RBCs (× 106/mm3)

3

3.2

3.8

4.1

3.2

4.6

Hb (g/dL)

8.5

9.2

9.5

10.1

9.4

9.2

Hematocrit (%)

28.9

30.2

30.9

30.4

29.5

30.2

MCV (fL)

70.5

69.6

71.4

65.4

72.4

74.6

MCH (pg)

25.4

22.4

25.6

24.6

26.1

25.9

MCHC (g/dL)

30.8

32.8

32.6

30.9

33.1

30.6

RDW (%)

18.6

17.5

16.9

17.5

18.4

18.6

TLC (× 103/mm3)

15.5

20.6

14.6

17.6

14.9

25.6

Platelets(× 103/mm3)

466

522

416

650

578

563

Reticulocytes (%)

6.5

5.4

10.2

8

4.5

5.5

Serum iron (μg/dL)

80

61

102

95

67

90

HbF (%)

80.2

84.6

74.02

66.4

70.2

88.4