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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Circular RNA SIPA1L1 promotes osteogenesis via regulating the miR-617/Smad3 axis in dental pulp stem cells

Fig. 5

MiR-617 directly targets Smad3. a The Venn plots showed predicted downstream genes binding miR-617. b, c Go annotation (b) and KEGG pathway analysis (c) showed the top 25 target genes and their enriched pathways. GO: A field directly related to reproduction. d Binding sequences in 3′UTR of miR-617 and Smad3 predicted online. The red letters represent the binding sequence of miR-617. Luciferase activity in 293T cells co-transfected with miR-617 mimics/NC and wild-type/mutant-type smad3, respectively. GO: Gene ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes

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Stem Cell Research & Therapy

ISSN: 1757-6512