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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

Fig. 2

SIRT1-modified hUCMSCs inhibited TGF-β1-induced EMT in Met-5A cells. qRT-PCR was used to measure the mRNA levels of Fibronectin (a), α-SMA (b), Snail (c), and E-cadherin (d) in the indicated conditions. e Western blot was used to measure the protein levels of Fibronectin, α-SMA, Snail, and E-cadherin in the indicated conditions, and the relative expressions were normalized to control (f). Data are presented as mean ± SD. n = 8 for each group. *p < 0.05, **p < 0.01, and ***p < 0.001 between the indicated groups

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Stem Cell Research & Therapy

ISSN: 1757-6512