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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

Fig. 3

SIRT1-modified hUCMSCs attenuated PD-induced peritoneal fibrosis and peritoneal functional injury. a Representative Masson’s trichrome staining of the peritoneum in the indicated groups (bar 200 μm). b Mean peritoneal membrane thickness of the submesothelial compact zone in the indicated groups. c Ultrafiltration volume in the indicated groups. d Dialysate creatinine concentration compared to plasma creatinine concentration from different groups. e Dialysate fluid glucose concentration compared to peritoneal dialysate fluid glucose concentration from different groups. Data are presented as mean ± SD. n = 8 for each group. *p < 0.05 and **p < 0.01 between the indicated groups

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