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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

Fig. 6

SIRT1-modified hUCMSCs inhibited the TGF-β/Smad3 pathway in PD-induced peritoneal damage. qRT-PCR was used to measure the mRNA levels of SIRT1 (a) and TGF-β (b) in the peritoneal omentum tissues from the indicated groups. c Western blot was used to measure the protein expressions of SIRT1, TGF-β, pSmad3, and Smad3 in the peritoneal omentum tissues from the indicated groups. d, e The relative expressions were normalized to control. Data are presented as mean ± SD. n = 8 for each group. *p < 0.05, **p < 0.01, and ***p < 0.001 between the indicated groups

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Stem Cell Research & Therapy

ISSN: 1757-6512